Bilateral simultaneous acute angle closure in an adult Nepalese woman

  • Sabin Sahu Sagarmatha Chaudhary Eye Hospital, Lahan, Nepal http://orcid.org/0000-0002-8500-9711
  • Lila Raj Puri Sagarmatha Chaudhary Eye Hospital, Lahan, Nepal
Keywords: acute angle closure, bilateral simultaneous, secondary cause

Abstract

Purpose: To report a case of bilateral simultaneous angle closure in an adult Nepalese woman without any known secondary cause.

Methods: Observational case report.

Results: A 50-year-old Nepalese woman presented with decreased vision, pain, redness, and watering in both eyes with associated coloured haloes, nausea, and vomiting for 10 days. At presentation, her visual acuity was 20/400 in the right eye and hand motions close to face with accurate projection of rays in the left eye. Intraocular pressure was 38 mmHg in the right eye and 48 mmHg in the left eye without any antiglaucoma medications. A slit-lamp examination revealed bilateral circum-corneal conjunctival congestion, corneal edema, and shallow anterior chambers. Both pupils were mid-dilated and non-reactive to light. Gonioscopy showed closed angles in all four quadrants bilaterally. Posterior segment examination revealed normal optic disc with cup-disc-ratio of 0.3 in the right eye, and blurring of disc margin with cup-disc-ratio of 0.3 in the left eye. The patient was started on systemic acetazolamide 250 mg 4 times a day, topical brimonidine 0.2% and timolol 0.5% 2 times a day, and topical dexamethasone 6 times a day in both eyes, following which IOP reduced to 11 and 12 mmHg, respectively, the corneal edema subsided, but the anterior chamber remained shallow. Laser peripheral iridotomy was performed in the right eye and surgical peripheral iridectomy was performed in the left eye. After two weeks, vision improved to 20/30 in both eyes with normal intraocular pressure off antiglaucoma medications. Anterior chambers deepened significantly with clear corneas bilaterally. Gonioscopy at this stage showed essentially open angles with appositional closure in superior and temporal quadrants in the right eye and open angles in all four quadrants in the left eye. Posterior segment evaluation revealed normal optic disc in both eyes.

Conclusions: Bilateral simultaneous acute angle closure is a rare presentation with very few reported secondary causes. We report a case of bilateral simultaneous angle closure in an adult Nepalese woman without any known secondary cause. The case was successfully managed with laser peripheral iridotomy in the right eye and surgical peripheral iridectomy in the left eye.

 

Author Biographies

Sabin Sahu, Sagarmatha Chaudhary Eye Hospital, Lahan, Nepal
Ophthalmology, Ophthalmologist
Lila Raj Puri, Sagarmatha Chaudhary Eye Hospital, Lahan, Nepal
Ophthalmology, Ophthalmologist

References

1. Tripathi RC, Tripathi JB, Haggerty C. Drug Induced glaucomas: mechanism and management. Drug Saf. 2003;26:749–67.
2. Ates H, Kayikcioglu O, Andac K. Bilateral angle closure glaucoma following general anesthesia. Int Ophthalmol. 1999;23:129–30.
3. Srinivasan R, Kaliaperumal S, Dutta TK. Bilateral angle closure glaucoma following snake bite. J Assoc Physicians India. 2005;53:46–48.
4. Kaushik S, Sachdev N, Pandav SS, Gupta A, Ram J. Bilateral acute angle closure glaucoma as a presentation of isolated microspherophakia in an adult: case report. BMC Ophthalmol. 2006;6:29.
5. Kimura R, Sakai M, Otabe H. Transient shallow anterior chamber as initial symptom in Harada's syndrome. Arch Ophthalmol. 1981;99:1604–1606.
6. Levy J, Yagev R, Petrova A, Lifshitz T. Topiramate-induced bilateral angle-closure glaucoma. Can J Ophthalmol. 2006;41:221-5.
7. Cruciani F, Lorenzatti M, Nazzarro V, Abdolrahimzadeh S. Bilateral acute angle closure glaucoma and myopia induced by topiramate. Clin Ter. 2009;160:215-216.
8. Grewal DS, Goldstein DA, Khatana AK, Tanna AP. Bilateral angle closure following use of a weight loss combination agent containing topiramate. J Glaucoma. 2015;24:132-136.
9. Lee GC, Tam CP, Danesh-Meyer HV, Myers JS, Katz LJ. Bilateral angle closure glaucoma induced by sulphonamide-derived medications. Clin Experiment Ophthalmol. 2007;35:55-58.
10. Foster PJ. The epidemiology of primary angle closure and associated glaucomatous optic neuropathy. Semin Ophthalmol. 2002 Jun;17: 50-58.
11. Seah SK, Foster PJ, Chew PT, Jap A, Oen F, Fam HB, Lim AS. Incidence of acute primary angle - closure glaucoma in Singapore. An island-wide survey. Arch Ophthalmol. 1997; 115:1436-1440.
Published
2018-10-23
How to Cite
Sahu, S., & Puri, L. (2018). Bilateral simultaneous acute angle closure in an adult Nepalese woman. Asian Journal of Ophthalmology, 16(1), 51-54. https://doi.org/10.35119/asjoo.v16i1.348
Section
Case Reports/Case Series