Visual outcomes in Patients with Diabetic Macular Oedema undergoing Cataract Surgery with or without Intravitreal Bevacizumab

  • Mazhar Hassan Hassan Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
  • Aziz Ur Rehman Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
  • Umair Qidwai Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
  • Rashid Alvi Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
  • Nasir Bhatti Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
  • Ashraf Dawood Al-Ibrahim Eye Hospital/Isra Postgraduate Institute of Ophthalmology, Karachi
Keywords: Bevacizumab, Macular edema, Visual acuity

Abstract

Aims: To evaluate the efficacy of a single intravitreal bevacizumab injection after cataract surgery for the management of postoperative decrease in vision in patients with diabetic macular oedema.
Methods: In this randomised controlled open-label parallel group study of 60 patients with diabetic macular oedema and lens opacity (grade ≥3), 30 eyes received a single intravitreal bevacizumab injection after cataract surgery, and 30 control eyes did not receive bevacizumab. The primary endpoint was change in best-corrected visual acuity 6 weeks after operation compared with that at baseline using the Snellen visual acuity chart.
Results: Postoperative visual acuity was significantly different between the group receiving bevacizumab and the control group (p<0.005). All patients in the bevacizumab group had postoperative visual acuities above 6/18 with 27 patients having visual acuities of 6/12 or better compared with 6 patients in the control group. None of the patients in the bevacizumab group had visual acuities less than 6/18 compared with 11 patients in the control group.
Conclusion: Intravitreal bevacizumab after cataract surgery appears to be beneficial for preventing postoperative visual loss in eyes with diabetic retinopathy by reducing the risk of macular thickening.

How to Cite
Hassan, M., Rehman, A., Qidwai, U., Alvi, R., Bhatti, N., & Dawood, A. (1). Visual outcomes in Patients with Diabetic Macular Oedema undergoing Cataract Surgery with or without Intravitreal Bevacizumab. Asian Journal of Ophthalmology, 12(3), 135-139. https://doi.org/10.35119/asjoo.v12i3.300
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Original Articles